Serotonergic Modulation of Nigrostriatal and Mesolimbic Dopamine and Motor/Exploratory Behaviors in the Rat

Purpose: The 5-HT(2A) receptor (R) is known to modulate dopamine (DA) release in the mammalian brain. Altanserin (ALT) and 2,5-dimethoxy-4-iodoamphetamine (DOI) act as 5-HT(2A)R antagonist and agonist, respectively. In the present study, we assessed the effects of ALT and DOI on motor and explorator...

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Detalles Bibliográficos
Autores principales: Nikolaus, Susanne, Wittsack, Hans-Jörg, Antke, Christina, Beu, Markus, Hautzel, Hubertus, Decheva, Cvetana, Mamlins, Eduards, Mori, Yuriko, Huston, Joseph P., Antoch, Gerald, Müller, Hans-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387951/
https://www.ncbi.nlm.nih.gov/pubmed/34456668
http://dx.doi.org/10.3389/fnins.2021.682398

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