Copper-64-Labeled Antibody Fragments for Immuno-PET/Radioimmunotherapy with Low Renal Radioactivity Levels and Amplified Tumor-Kidney Ratios

[Image: see text] Copper-64 ((64)Cu)-labeled antibody fragments such as Fab are useful for molecular imaging (immuno-PET) and radioimmunotherapy. However, these fragments cause high and persistent localization of radioactivity in the kidneys after injection. To solve this problem, this study assesse...

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Detalles Bibliográficos
Autores principales: Suzuki, Hiroyuki, Kise, Shota, Kaizuka, Yuta, Watanabe, Reo, Sugawa, Tsubasa, Furukawa, Takako, Fujii, Hirofumi, Uehara, Tomoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388099/
https://www.ncbi.nlm.nih.gov/pubmed/34471758
http://dx.doi.org/10.1021/acsomega.1c02516

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