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Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review

BACKGROUND: Vascularized omental lymphatic transplant (VOLT) is an increasingly popular treatment of extremity lymphedema given its promising donor site. While the success of VOLT in the treatment of lymphedema has been reported previously, several questions remain. AIM: To further elucidate appropr...

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Autores principales: Jarvis, Nicholas R., Torres, Ricardo A., Avila, Francisco R., Forte, Antonio J., Rebecca, Alanna M., Teven, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388172/
https://www.ncbi.nlm.nih.gov/pubmed/33826249
http://dx.doi.org/10.1002/cnr2.1370
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author Jarvis, Nicholas R.
Torres, Ricardo A.
Avila, Francisco R.
Forte, Antonio J.
Rebecca, Alanna M.
Teven, Chad M.
author_facet Jarvis, Nicholas R.
Torres, Ricardo A.
Avila, Francisco R.
Forte, Antonio J.
Rebecca, Alanna M.
Teven, Chad M.
author_sort Jarvis, Nicholas R.
collection PubMed
description BACKGROUND: Vascularized omental lymphatic transplant (VOLT) is an increasingly popular treatment of extremity lymphedema given its promising donor site. While the success of VOLT in the treatment of lymphedema has been reported previously, several questions remain. AIM: To further elucidate appropriate use of VOLT in the treatment of lymphedema, specifically addressing patient selection, harvest technique, and operative methods. METHODS AND RESULTS: A systematic review of VOLT for upper extremity lymphedema was performed. Of 115 yield studies, seven were included for analysis based on inclusion and exclusion criteria. Included studies demonstrated significant reductions in extremity circumference/volume (average volume reduction, 22.7%‐39.5%) as well as subjective improvements using patient‐reported outcomes. Though studies are heterogenous and limited, when analyzed in aggregate, suggest the efficacy of VOLT in lymphedema treatment. CONCLUSION: This is the largest systematic review of VOLT to date. VOLT continues to show promise as a safe and efficacious surgical intervention for lymphedema in the upper extremity. Further studies are warranted to more definitively identify patients for whom this technique is appropriate as well as ideal harvest and inset technique.
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spelling pubmed-83881722021-08-31 Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review Jarvis, Nicholas R. Torres, Ricardo A. Avila, Francisco R. Forte, Antonio J. Rebecca, Alanna M. Teven, Chad M. Cancer Rep (Hoboken) Systematic Review BACKGROUND: Vascularized omental lymphatic transplant (VOLT) is an increasingly popular treatment of extremity lymphedema given its promising donor site. While the success of VOLT in the treatment of lymphedema has been reported previously, several questions remain. AIM: To further elucidate appropriate use of VOLT in the treatment of lymphedema, specifically addressing patient selection, harvest technique, and operative methods. METHODS AND RESULTS: A systematic review of VOLT for upper extremity lymphedema was performed. Of 115 yield studies, seven were included for analysis based on inclusion and exclusion criteria. Included studies demonstrated significant reductions in extremity circumference/volume (average volume reduction, 22.7%‐39.5%) as well as subjective improvements using patient‐reported outcomes. Though studies are heterogenous and limited, when analyzed in aggregate, suggest the efficacy of VOLT in lymphedema treatment. CONCLUSION: This is the largest systematic review of VOLT to date. VOLT continues to show promise as a safe and efficacious surgical intervention for lymphedema in the upper extremity. Further studies are warranted to more definitively identify patients for whom this technique is appropriate as well as ideal harvest and inset technique. John Wiley and Sons Inc. 2021-04-07 /pmc/articles/PMC8388172/ /pubmed/33826249 http://dx.doi.org/10.1002/cnr2.1370 Text en © 2021 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Systematic Review
Jarvis, Nicholas R.
Torres, Ricardo A.
Avila, Francisco R.
Forte, Antonio J.
Rebecca, Alanna M.
Teven, Chad M.
Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title_full Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title_fullStr Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title_full_unstemmed Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title_short Vascularized omental lymphatic transplant for upper extremity lymphedema: A systematic review
title_sort vascularized omental lymphatic transplant for upper extremity lymphedema: a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388172/
https://www.ncbi.nlm.nih.gov/pubmed/33826249
http://dx.doi.org/10.1002/cnr2.1370
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