NK cells enhance CAR-T cell antitumor efficacy by enhancing immune/tumor cells cluster formation and improving CAR-T cell fitness

BACKGROUND: Chimeric antigen receptor (CAR)-T cell immunotherapy has modified the concept of treatment in hematological malignancies. In comparison with pediatric patients, where responses are maintained over many years, older patients, such as those with non-Hodgkin’s lymphoma (NHL) and multiple my...

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Detalles Bibliográficos
Autores principales: Bachiller, Mireia, Perez-Amill, Lorena, Battram, Anthony Matthew, Carné, Sebastian Ciro, Najjar, Amer, Verhoeyen, Els, Juan, Manel, Urbano-Ispizua, Alvaro, Martin-Antonio, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388291/
https://www.ncbi.nlm.nih.gov/pubmed/34433634
http://dx.doi.org/10.1136/jitc-2021-002866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388291/
https://www.ncbi.nlm.nih.gov/pubmed/34433634
http://dx.doi.org/10.1136/jitc-2021-002866

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