Spray-Dried Plasma Improves Body Weight, Intestinal Barrier Function, and Tibia Strength during Experimental Constant Heat Stress Conditions

SIMPLE SUMMARY: Broilers are especially heat sensitive because of the absence of sweat glands and their elevated metabolism. Under commercial conditions, extremely high temperatures (heat stress) reduce their performance. This research aimed to assess spray-dried feeding plasma (SDP) during constant heat stress (HS) on the performance, intestinal permeability, and bone strength in broilers. Chickens fed with a diet supplemented with SDP increased both their body weight and body weight gain compared to the HS control group. At the end of the study (d 42 of age), chickens fed with SDP significantly alleviated the increased gut leakage induced by HS and showed a significant increase in tibia strength compared with control HS chickens. The results in the present study suggest SDP mends gut integrity, hence reducing chronic systemic inflammation. ABSTRACT: The aim of this study was to see how spray-dried plasma (SDP) supplementation affected broiler chicken performance, intestinal permeability, and bone strength during persistent heat stress. One-day-old chicks (n = 480) were randomly assigned into twelve environmental corrals; four thermoneutral (TN-negative control, maintained at 24 °C from d 21–42); four heat stress (HS, exposed to 35 °C from d 21–42); and four heat stress treated with 2% SDP in the feed until d 28 followed by 1% SDP until d 42 (HS-SDP). The performance and serum levels of fluorescein isothiocyanate-dextran (FITC-d) were evaluated at d 21, 28, 35, and 42. The tibias strength was evaluated on d 21 and 42. The increment in chicken temperature (p < 0.05) was observed two h following the increase in environmental temperature in both HS groups and was associated with decreased performance parameters compared with the TN group. At d 42 of age, the chickens exposed to HS had an impaired gut permeability and decreased tibia strength compared to the TN group (p < 0.05). However, partially feeding SDP mitigated these adverse effects significantly. These findings imply that using SDP strategically during stressful times, such as prolonged heat stress, may help mitigate its negative consequences.