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Apply a Physiologically Based Pharmacokinetic Model to Promote the Development of Enrofloxacin Granules: Predict Withdrawal Interval and Toxicity Dose
Enrofloxacin (ENR) granules were developed to prevent and control the infections caused by foodborne zoonotic intestinal pathogens in our previous studies. To promote the further development of ENR granules and standardize their usage in pigs, a physiologically based pharmacokinetic (PBPK) model of...
Autores principales: | Zhou, Kaixiang, Liu, Aimei, Ma, Wenjin, Sun, Lei, Mi, Kun, Xu, Xiangyue, Algharib, Samah Attia, Xie, Shuyu, Huang, Lingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388861/ https://www.ncbi.nlm.nih.gov/pubmed/34439005 http://dx.doi.org/10.3390/antibiotics10080955 |
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