Unripe Carica papaya Protects Methylglyoxal-Invoked Endothelial Cell Inflammation and Apoptosis via the Suppression of Oxidative Stress and Akt/MAPK/NF-κB Signals

Methylglyoxal (MGO), a highly reactive dicarbonyl compound, causes endothelial oxidative stress and vascular complications in diabetes. Excessive MGO-induced ROS production triggers eNOS uncoupling, inflammatory responses, and cell death signaling cascades. Our previous study reported that unripe Ca...

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Detalles Bibliográficos
Autores principales: Jarisarapurin, Wattanased, Kunchana, Khwandow, Chularojmontri, Linda, Wattanapitayakul, Suvara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388906/
https://www.ncbi.nlm.nih.gov/pubmed/34439407
http://dx.doi.org/10.3390/antiox10081158

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