GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation

Sepsis causes high mortality in the setting of septic shock. LEADER and other trials revealed cardioprotective and anti-inflammatory properties of glucagon-like peptide-1 (GLP-1) analogs like liraglutide (Lira). We previously demonstrated improved survival in lipopolysaccharide (LPS)-induced endotox...

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Detalles Bibliográficos
Autores principales: Helmstädter, Johanna, Keppeler, Karin, Aust, Franziska, Küster, Leonie, Frenis, Katie, Filippou, Konstantina, Vujacic-Mirski, Ksenija, Tsohataridis, Simeon, Kalinovic, Sanela, Kröller-Schön, Swenja, Oelze, Matthias, Bosmann, Markus, Münzel, Thomas, Daiber, Andreas, Steven, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388926/
https://www.ncbi.nlm.nih.gov/pubmed/34439423
http://dx.doi.org/10.3390/antiox10081175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388926/
https://www.ncbi.nlm.nih.gov/pubmed/34439423
http://dx.doi.org/10.3390/antiox10081175

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