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GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation
Sepsis causes high mortality in the setting of septic shock. LEADER and other trials revealed cardioprotective and anti-inflammatory properties of glucagon-like peptide-1 (GLP-1) analogs like liraglutide (Lira). We previously demonstrated improved survival in lipopolysaccharide (LPS)-induced endotox...
Autores principales: | Helmstädter, Johanna, Keppeler, Karin, Aust, Franziska, Küster, Leonie, Frenis, Katie, Filippou, Konstantina, Vujacic-Mirski, Ksenija, Tsohataridis, Simeon, Kalinovic, Sanela, Kröller-Schön, Swenja, Oelze, Matthias, Bosmann, Markus, Münzel, Thomas, Daiber, Andreas, Steven, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388926/ https://www.ncbi.nlm.nih.gov/pubmed/34439423 http://dx.doi.org/10.3390/antiox10081175 |
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