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Melatonin Prevents Chronic Kidney Disease-Induced Hypertension in Young Rat Treated with Adenine: Implications of Gut Microbiota-Derived Metabolites

Melatonin, a signaling hormone with pleiotropic biofunctions, has shown health benefits. Trimethylamine-N-oxide (TMAO) and asymmetric dimethylarginine (ADMA) are uremic toxins involved in the development of hypertension. TMAO originates from trimethylamine (TMA), a gut microbial product. ADMA is an...

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Detalles Bibliográficos
Autores principales:	Hsu, Chien-Ning, Yang, Hung-Wei, Hou, Chih-Yao, Chang-Chien, Guo-Ping, Lin, Sufan, Tain, You-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388963/ https://www.ncbi.nlm.nih.gov/pubmed/34439458 http://dx.doi.org/10.3390/antiox10081211

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