A Combined Drug Treatment That Reduces Mitochondrial Iron and Reactive Oxygen Levels Recovers Insulin Secretion in NAF-1-Deficient Pancreatic Cells

Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen species (ROS), the development of diabetes associated wit...

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Detalles Bibliográficos
Autores principales: Karmi, Ola, Sohn, Yang-Sung, Marjault, Henri-Baptiste, Israeli, Tal, Leibowitz, Gil, Ioannidis, Konstantinos, Nahmias, Yaakov, Mittler, Ron, Cabantchik, Ioav Z., Nechushtai, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388971/
https://www.ncbi.nlm.nih.gov/pubmed/34439408
http://dx.doi.org/10.3390/antiox10081160

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