Mycobacterium tuberculosis H(2)S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

H(2)S is a potent gasotransmitter in eukaryotes and bacteria. Host-derived H(2)S has been shown to profoundly alter M. tuberculosis (Mtb) energy metabolism and growth. However, compelling evidence for endogenous production of H(2)S and its role in Mtb physiology is lacking. We show that multidrug-re...

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Detalles Bibliográficos
Autores principales: Kunota, Tafara T. R., Rahman, Md. Aejazur, Truebody, Barry E., Mackenzie, Jared S., Saini, Vikram, Lamprecht, Dirk A., Adamson, John H., Sevalkar, Ritesh R., Lancaster, Jack R., Berney, Michael, Glasgow, Joel N., Steyn, Adrie J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389258/
https://www.ncbi.nlm.nih.gov/pubmed/34439535
http://dx.doi.org/10.3390/antiox10081285

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