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Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress

Primary cilia (PC) are microtubule-based protrusions of the cell membrane transducing molecular signals during brain development. Here, we report that PC are required for maintenance of Substantia nigra (SN) dopaminergic (DA) neurons highly vulnerable in Parkinson’s disease (PD). Targeted blockage o...

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Detalles Bibliográficos
Autores principales:	Mustafa, Rasem, Rawas, Chahinaz, Mannal, Nadja, Kreiner, Grzegorz, Spittau, Björn, Kamińska, Katarzyna, Yilmaz, Rüstem, Pötschke, Christina, Kirsch, Joachim, Liss, Birgit, Tucker, Kerry L., Parlato, Rosanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389284/ https://www.ncbi.nlm.nih.gov/pubmed/34439532 http://dx.doi.org/10.3390/antiox10081284

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