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Kinetic Analysis of Lidocaine Elimination by Pig Liver Cells Cultured in 3D Multi-Compartment Hollow Fiber Membrane Network Perfusion Bioreactors

Liver cells cultured in 3D bioreactors is an interesting option for temporary extracorporeal liver support in the treatment of acute liver failure and for animal models for preclinical drug screening. Bioreactor capacity to eliminate drugs is generally used for assessing cell metabolic competence in...

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Detalles Bibliográficos
Autores principales:	Catapano, Gerardo, Unger, Juliane K., Zanetti, Elisabetta M., Fragomeni, Gionata, Gerlach, Jörg C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389311/ https://www.ncbi.nlm.nih.gov/pubmed/34436107 http://dx.doi.org/10.3390/bioengineering8080104

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