A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5

Tumor necrosis factor receptor-1 (TNFR1) signaling, apart from its pleiotropic functions in inflammation, plays a role in embryogenesis as deficiency of varieties of its downstream molecules leads to embryonic lethality in mice. Caspase-8 noncleavable receptor interacting serine/threonine kinase 1 (...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Huang, Kai, Zhang, Yuxia, Han, Tao, Li, Lang, Ruan, Chenchen, Sun, Ye-hsuan, Shi, Wenke, Han, Wei, Wu, Su-qin, Song, Jing, Liu, Jun, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389420/
https://www.ncbi.nlm.nih.gov/pubmed/34437534
http://dx.doi.org/10.1371/journal.pbio.3001304

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