Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression

The systematic identification of genetic events driving cellular transformation and tumor progression in the absence of a highly recurrent oncogenic driver mutation is a challenge in cutaneous oncology. In cutaneous squamous cell carcinoma (cuSCC), the high UV-induced mutational burden poses a hurdl...

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Detalles Bibliográficos
Autores principales: Aiderus, Aziz, Newberg, Justin Y., Guzman-Rojas, Liliana, Contreras-Sandoval, Ana M., Meshey, Amanda L., Jones, Devin J., Amaya-Manzanares, Felipe, Rangel, Roberto, Ward, Jerrold M., Lee, Song-Choon, Ban, Kenneth Hon-Kim, Rogers, Keith, Rogers, Susan M., Selvanesan, Luxmanan, McNoe, Leslie A., Copeland, Neal G., Jenkins, Nancy A., Tsai, Kenneth Y., Black, Michael A., Mann, Karen M., Mann, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389471/
https://www.ncbi.nlm.nih.gov/pubmed/34398873
http://dx.doi.org/10.1371/journal.pgen.1009094

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