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Olfactory perceptual decision-making is biased by motivational state
Growing evidence suggests that internal factors influence how we perceive the world. However, it remains unclear whether and how motivational states, such as hunger and satiety, regulate perceptual decision-making in the olfactory domain. Here, we developed a novel behavioral task involving mixtures...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389475/ https://www.ncbi.nlm.nih.gov/pubmed/34437533 http://dx.doi.org/10.1371/journal.pbio.3001374 |
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author | Shanahan, Laura K. Bhutani, Surabhi Kahnt, Thorsten |
author_facet | Shanahan, Laura K. Bhutani, Surabhi Kahnt, Thorsten |
author_sort | Shanahan, Laura K. |
collection | PubMed |
description | Growing evidence suggests that internal factors influence how we perceive the world. However, it remains unclear whether and how motivational states, such as hunger and satiety, regulate perceptual decision-making in the olfactory domain. Here, we developed a novel behavioral task involving mixtures of food and nonfood odors (i.e., cinnamon bun and cedar; pizza and pine) to assess olfactory perceptual decision-making in humans. Participants completed the task before and after eating a meal that matched one of the food odors, allowing us to compare perception of meal-matched and non-matched odors across fasted and sated states. We found that participants were less likely to perceive meal-matched, but not non-matched, odors as food dominant in the sated state. Moreover, functional magnetic resonance imaging (fMRI) data revealed neural changes that paralleled these behavioral effects. Namely, odor-evoked fMRI responses in olfactory/limbic brain regions were altered after the meal, such that neural patterns for meal-matched odor pairs were less discriminable and less food-like than their non-matched counterparts. Our findings demonstrate that olfactory perceptual decision-making is biased by motivational state in an odor-specific manner and highlight a potential brain mechanism underlying this adaptive behavior. |
format | Online Article Text |
id | pubmed-8389475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-83894752021-08-27 Olfactory perceptual decision-making is biased by motivational state Shanahan, Laura K. Bhutani, Surabhi Kahnt, Thorsten PLoS Biol Research Article Growing evidence suggests that internal factors influence how we perceive the world. However, it remains unclear whether and how motivational states, such as hunger and satiety, regulate perceptual decision-making in the olfactory domain. Here, we developed a novel behavioral task involving mixtures of food and nonfood odors (i.e., cinnamon bun and cedar; pizza and pine) to assess olfactory perceptual decision-making in humans. Participants completed the task before and after eating a meal that matched one of the food odors, allowing us to compare perception of meal-matched and non-matched odors across fasted and sated states. We found that participants were less likely to perceive meal-matched, but not non-matched, odors as food dominant in the sated state. Moreover, functional magnetic resonance imaging (fMRI) data revealed neural changes that paralleled these behavioral effects. Namely, odor-evoked fMRI responses in olfactory/limbic brain regions were altered after the meal, such that neural patterns for meal-matched odor pairs were less discriminable and less food-like than their non-matched counterparts. Our findings demonstrate that olfactory perceptual decision-making is biased by motivational state in an odor-specific manner and highlight a potential brain mechanism underlying this adaptive behavior. Public Library of Science 2021-08-26 /pmc/articles/PMC8389475/ /pubmed/34437533 http://dx.doi.org/10.1371/journal.pbio.3001374 Text en © 2021 Shanahan et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Shanahan, Laura K. Bhutani, Surabhi Kahnt, Thorsten Olfactory perceptual decision-making is biased by motivational state |
title | Olfactory perceptual decision-making is biased by motivational state |
title_full | Olfactory perceptual decision-making is biased by motivational state |
title_fullStr | Olfactory perceptual decision-making is biased by motivational state |
title_full_unstemmed | Olfactory perceptual decision-making is biased by motivational state |
title_short | Olfactory perceptual decision-making is biased by motivational state |
title_sort | olfactory perceptual decision-making is biased by motivational state |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389475/ https://www.ncbi.nlm.nih.gov/pubmed/34437533 http://dx.doi.org/10.1371/journal.pbio.3001374 |
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