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Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood–brain barrier during kainic acid-induced brain damage

Rufinamide (RUF) is a structurally unique anti-epileptic drug, but its protective mechanism against brain injury remains unclear. In the present study, we validated how the RUF protected mice with kainic acid (KA)-induced neuronal damage. To achieve that, a mouse epilepsy model was established by KA...

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Detalles Bibliográficos
Autores principales: Yu, Huaxu, He, Bin, Han, Xu, Yan, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389504/
https://www.ncbi.nlm.nih.gov/pubmed/34514163
http://dx.doi.org/10.1515/biol-2021-0090

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