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Metformin Therapy Effects on the Expression of Sodium-Glucose Cotransporter 2, Leptin, and SIRT6 Levels in Pericoronary Fat Excised from Pre-Diabetic Patients with Acute Myocardial Infarction

Background and purpose: pericoronary fat over-inflammation might lead to the development and destabilization of coronary plaque in patients with pre-diabetes (PDM). Notably, pericoronary fat could over-express the sodium-glucose cotransporter 2 (SGLT2) and leptin, along with decreased sirtuin 6 (SIR...

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Detalles Bibliográficos
Autores principales:	Sardu, Celestino, D’Onofrio, Nunzia, Torella, Michele, Portoghese, Michele, Mureddu, Simone, Loreni, Francesco, Ferraraccio, Franca, Panarese, Iacopo, Trotta, Maria Consiglia, Gatta, Gianluca, Galdiero, Marilena, Sasso, Ferdinando Carlo, D’Amico, Michele, De Feo, Marisa, Balestrieri, Maria Luisa, Paolisso, Giuseppe, Marfella, Raffaele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389537/ https://www.ncbi.nlm.nih.gov/pubmed/34440108 http://dx.doi.org/10.3390/biomedicines9080904

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