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Pharmacologically Inhibiting Glycogen Synthase Kinase-3β Ameliorates Renal Inflammation and Nephrotoxicity in an Animal Model of Cisplatin-Induced Acute Kidney Injury

The adverse effect of cisplatin administration causes acute kidney injury (AKI) following renal inflammation and nephrotoxicity, characterized by proximal tubular cell apoptosis and necrosis. Pro-apoptotic and pro-inflammatory roles of glycogen synthase kinase (GSK)-3β have been reported. This study...

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Detalles Bibliográficos
Autores principales: Hsing, Chung-Hsi, Tsai, Cheng-Chieh, Chen, Chia-Ling, Lin, Yu-Hui, Tseng, Po-Chun, Satria, Rahmat Dani, Lin, Chiou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389561/
https://www.ncbi.nlm.nih.gov/pubmed/34440091
http://dx.doi.org/10.3390/biomedicines9080887

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