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Pharmacologically Inhibiting Glycogen Synthase Kinase-3β Ameliorates Renal Inflammation and Nephrotoxicity in an Animal Model of Cisplatin-Induced Acute Kidney Injury
The adverse effect of cisplatin administration causes acute kidney injury (AKI) following renal inflammation and nephrotoxicity, characterized by proximal tubular cell apoptosis and necrosis. Pro-apoptotic and pro-inflammatory roles of glycogen synthase kinase (GSK)-3β have been reported. This study...
Autores principales: | Hsing, Chung-Hsi, Tsai, Cheng-Chieh, Chen, Chia-Ling, Lin, Yu-Hui, Tseng, Po-Chun, Satria, Rahmat Dani, Lin, Chiou-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389561/ https://www.ncbi.nlm.nih.gov/pubmed/34440091 http://dx.doi.org/10.3390/biomedicines9080887 |
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