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Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the accumulation of extracellular plaques composed by amyloid-β (Aβ) and intracellular neurofibrillary tangles of hyperphosphorylated tau. AD-related neurodegenerative mechanisms involve early changes of mitochondria-associated endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales:	Fernandes, Tânia, Resende, Rosa, Silva, Diana F., Marques, Ana P., Santos, Armanda E., Cardoso, Sandra M., Domingues, M. Rosário, Moreira, Paula I., Pereira, Cláudia F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389659/ https://www.ncbi.nlm.nih.gov/pubmed/34440085 http://dx.doi.org/10.3390/biomedicines9080881

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