Aldehyde Dehydrogenase Mutation Exacerbated High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease with Gut Microbiota Remodeling in Male Mice

SIMPLE SUMMARY: ALDH2, mitochondrial aldehyde dehydrogenase 2, is a critical enzyme involved in ethanol clearance in acetaldehyde metabolism. The prevalence of the ALDH2*2 variant is 45% in the Taiwanese population. ALDH2 reportedly has protective properties on myocardial damage, stroke, and diabeti...

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Detalles Bibliográficos
Autores principales: Yang, Sien-Sing, Chen, Yi-Hsun, Hu, Jui-Ting, Chiu, Ching-Feng, Hung, Shao-Wen, Chang, Yi-Chih, Chiu, Chien-Chao, Chuang, Hsiao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389693/
https://www.ncbi.nlm.nih.gov/pubmed/34439969
http://dx.doi.org/10.3390/biology10080737

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