Cargando…
The Relationship Between Vitamin D and Asthma Exacerbation
Asthma is a chronic airway inflammatory condition that affects millions of people worldwide. It presents with reversible bronchoconstriction that makes it difficult for patients to breathe. Asthma flare-ups have several triggers, but the symptoms are similar, including wheezing, coughing, shortness...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389855/ https://www.ncbi.nlm.nih.gov/pubmed/34462708 http://dx.doi.org/10.7759/cureus.17279 |
_version_ | 1783742956684967936 |
---|---|
author | Ogeyingbo, Opemipo D Ahmed, Rowan Gyawali, Mallika Venkatesan, Nanditha Bhandari, Renu Botleroo, Rinky A Kareem, Roaa Elshaikh, Abeer O |
author_facet | Ogeyingbo, Opemipo D Ahmed, Rowan Gyawali, Mallika Venkatesan, Nanditha Bhandari, Renu Botleroo, Rinky A Kareem, Roaa Elshaikh, Abeer O |
author_sort | Ogeyingbo, Opemipo D |
collection | PubMed |
description | Asthma is a chronic airway inflammatory condition that affects millions of people worldwide. It presents with reversible bronchoconstriction that makes it difficult for patients to breathe. Asthma flare-ups have several triggers, but the symptoms are similar, including wheezing, coughing, shortness of breath, and chest tightness. Severe asthma exacerbation is described as symptomatic asthma that is unresponsive to inhaled asthma medications and is only responsive to steroids in oral or intravenous forms. Asthma-related deaths occur during episodes of asthma exacerbation. Vitamin D is a steroid-derived vitamin produced by the body and found in some foods. Administration of doses of vitamin D can also help maintain an adequate level of the vitamin. Vitamin D plays a vital role in regulating the level of calcium in the body and bone remodeling processes. It also has an immunomodulatory effect on innate and adaptive immunity within the body and that partially explains its links to inflammation-induced epithelial changes seen in asthma. We conducted this literature review by selecting articles from PubMed and Cumulated Index to Nursing and Allied Health Literature (CINAHL) Plus databases to investigate the relationship between vitamin D level and asthma exacerbation. From the studies, we found that asthmatic patients have low vitamin D levels during an asthma exacerbation. However, supplementing vitamin D may not reduce the rates of asthma exacerbation except in adult asthmatic patients with low levels of vitamin D. |
format | Online Article Text |
id | pubmed-8389855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-83898552021-08-29 The Relationship Between Vitamin D and Asthma Exacerbation Ogeyingbo, Opemipo D Ahmed, Rowan Gyawali, Mallika Venkatesan, Nanditha Bhandari, Renu Botleroo, Rinky A Kareem, Roaa Elshaikh, Abeer O Cureus Internal Medicine Asthma is a chronic airway inflammatory condition that affects millions of people worldwide. It presents with reversible bronchoconstriction that makes it difficult for patients to breathe. Asthma flare-ups have several triggers, but the symptoms are similar, including wheezing, coughing, shortness of breath, and chest tightness. Severe asthma exacerbation is described as symptomatic asthma that is unresponsive to inhaled asthma medications and is only responsive to steroids in oral or intravenous forms. Asthma-related deaths occur during episodes of asthma exacerbation. Vitamin D is a steroid-derived vitamin produced by the body and found in some foods. Administration of doses of vitamin D can also help maintain an adequate level of the vitamin. Vitamin D plays a vital role in regulating the level of calcium in the body and bone remodeling processes. It also has an immunomodulatory effect on innate and adaptive immunity within the body and that partially explains its links to inflammation-induced epithelial changes seen in asthma. We conducted this literature review by selecting articles from PubMed and Cumulated Index to Nursing and Allied Health Literature (CINAHL) Plus databases to investigate the relationship between vitamin D level and asthma exacerbation. From the studies, we found that asthmatic patients have low vitamin D levels during an asthma exacerbation. However, supplementing vitamin D may not reduce the rates of asthma exacerbation except in adult asthmatic patients with low levels of vitamin D. Cureus 2021-08-18 /pmc/articles/PMC8389855/ /pubmed/34462708 http://dx.doi.org/10.7759/cureus.17279 Text en Copyright © 2021, Ogeyingbo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Ogeyingbo, Opemipo D Ahmed, Rowan Gyawali, Mallika Venkatesan, Nanditha Bhandari, Renu Botleroo, Rinky A Kareem, Roaa Elshaikh, Abeer O The Relationship Between Vitamin D and Asthma Exacerbation |
title | The Relationship Between Vitamin D and Asthma Exacerbation |
title_full | The Relationship Between Vitamin D and Asthma Exacerbation |
title_fullStr | The Relationship Between Vitamin D and Asthma Exacerbation |
title_full_unstemmed | The Relationship Between Vitamin D and Asthma Exacerbation |
title_short | The Relationship Between Vitamin D and Asthma Exacerbation |
title_sort | relationship between vitamin d and asthma exacerbation |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389855/ https://www.ncbi.nlm.nih.gov/pubmed/34462708 http://dx.doi.org/10.7759/cureus.17279 |
work_keys_str_mv | AT ogeyingboopemipod therelationshipbetweenvitamindandasthmaexacerbation AT ahmedrowan therelationshipbetweenvitamindandasthmaexacerbation AT gyawalimallika therelationshipbetweenvitamindandasthmaexacerbation AT venkatesannanditha therelationshipbetweenvitamindandasthmaexacerbation AT bhandarirenu therelationshipbetweenvitamindandasthmaexacerbation AT botleroorinkya therelationshipbetweenvitamindandasthmaexacerbation AT kareemroaa therelationshipbetweenvitamindandasthmaexacerbation AT elshaikhabeero therelationshipbetweenvitamindandasthmaexacerbation AT ogeyingboopemipod relationshipbetweenvitamindandasthmaexacerbation AT ahmedrowan relationshipbetweenvitamindandasthmaexacerbation AT gyawalimallika relationshipbetweenvitamindandasthmaexacerbation AT venkatesannanditha relationshipbetweenvitamindandasthmaexacerbation AT bhandarirenu relationshipbetweenvitamindandasthmaexacerbation AT botleroorinkya relationshipbetweenvitamindandasthmaexacerbation AT kareemroaa relationshipbetweenvitamindandasthmaexacerbation AT elshaikhabeero relationshipbetweenvitamindandasthmaexacerbation |