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Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
[Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-ra...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389888/ https://www.ncbi.nlm.nih.gov/pubmed/34232047 http://dx.doi.org/10.1021/acs.jpcb.1c01986 |
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author | Zheng, Bin Avni, Yael Andelman, David Podgornik, Rudolf |
author_facet | Zheng, Bin Avni, Yael Andelman, David Podgornik, Rudolf |
author_sort | Zheng, Bin |
collection | PubMed |
description | [Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-range interactions between the charged sites on the polymer chains as well as an association–dissociation energy parameter in the CR mechanism. We investigate the phase diagrams of two CR models: (i) the hopping CR model (HCR) and (ii) the asymmetric CR model (ACR). It is shown that during the phase separation that the polymers in the condensed phase are more charged than those in the dilute phase, in accordance with Le Chatelier’s principle. In addition, secondary CR effects also influence the change in the volume fraction of the two phases. The latter can cause the charge difference between the two phases to change nonmonotonically as a function of the CR parameters. |
format | Online Article Text |
id | pubmed-8389888 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-83898882021-08-31 Phase Separation of Polyelectrolytes: The Effect of Charge Regulation Zheng, Bin Avni, Yael Andelman, David Podgornik, Rudolf J Phys Chem B [Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-range interactions between the charged sites on the polymer chains as well as an association–dissociation energy parameter in the CR mechanism. We investigate the phase diagrams of two CR models: (i) the hopping CR model (HCR) and (ii) the asymmetric CR model (ACR). It is shown that during the phase separation that the polymers in the condensed phase are more charged than those in the dilute phase, in accordance with Le Chatelier’s principle. In addition, secondary CR effects also influence the change in the volume fraction of the two phases. The latter can cause the charge difference between the two phases to change nonmonotonically as a function of the CR parameters. American Chemical Society 2021-07-07 2021-07-22 /pmc/articles/PMC8389888/ /pubmed/34232047 http://dx.doi.org/10.1021/acs.jpcb.1c01986 Text en © 2021 American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Zheng, Bin Avni, Yael Andelman, David Podgornik, Rudolf Phase Separation of Polyelectrolytes: The Effect of Charge Regulation |
title | Phase Separation of Polyelectrolytes: The Effect of
Charge Regulation |
title_full | Phase Separation of Polyelectrolytes: The Effect of
Charge Regulation |
title_fullStr | Phase Separation of Polyelectrolytes: The Effect of
Charge Regulation |
title_full_unstemmed | Phase Separation of Polyelectrolytes: The Effect of
Charge Regulation |
title_short | Phase Separation of Polyelectrolytes: The Effect of
Charge Regulation |
title_sort | phase separation of polyelectrolytes: the effect of
charge regulation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389888/ https://www.ncbi.nlm.nih.gov/pubmed/34232047 http://dx.doi.org/10.1021/acs.jpcb.1c01986 |
work_keys_str_mv | AT zhengbin phaseseparationofpolyelectrolytestheeffectofchargeregulation AT avniyael phaseseparationofpolyelectrolytestheeffectofchargeregulation AT andelmandavid phaseseparationofpolyelectrolytestheeffectofchargeregulation AT podgornikrudolf phaseseparationofpolyelectrolytestheeffectofchargeregulation |