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Phase Separation of Polyelectrolytes: The Effect of Charge Regulation

[Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-ra...

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Autores principales: Zheng, Bin, Avni, Yael, Andelman, David, Podgornik, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389888/
https://www.ncbi.nlm.nih.gov/pubmed/34232047
http://dx.doi.org/10.1021/acs.jpcb.1c01986
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author Zheng, Bin
Avni, Yael
Andelman, David
Podgornik, Rudolf
author_facet Zheng, Bin
Avni, Yael
Andelman, David
Podgornik, Rudolf
author_sort Zheng, Bin
collection PubMed
description [Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-range interactions between the charged sites on the polymer chains as well as an association–dissociation energy parameter in the CR mechanism. We investigate the phase diagrams of two CR models: (i) the hopping CR model (HCR) and (ii) the asymmetric CR model (ACR). It is shown that during the phase separation that the polymers in the condensed phase are more charged than those in the dilute phase, in accordance with Le Chatelier’s principle. In addition, secondary CR effects also influence the change in the volume fraction of the two phases. The latter can cause the charge difference between the two phases to change nonmonotonically as a function of the CR parameters.
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spelling pubmed-83898882021-08-31 Phase Separation of Polyelectrolytes: The Effect of Charge Regulation Zheng, Bin Avni, Yael Andelman, David Podgornik, Rudolf J Phys Chem B [Image: see text] Complex coacervation, known as the liquid–liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the complex coacervation by including short-range interactions between the charged sites on the polymer chains as well as an association–dissociation energy parameter in the CR mechanism. We investigate the phase diagrams of two CR models: (i) the hopping CR model (HCR) and (ii) the asymmetric CR model (ACR). It is shown that during the phase separation that the polymers in the condensed phase are more charged than those in the dilute phase, in accordance with Le Chatelier’s principle. In addition, secondary CR effects also influence the change in the volume fraction of the two phases. The latter can cause the charge difference between the two phases to change nonmonotonically as a function of the CR parameters. American Chemical Society 2021-07-07 2021-07-22 /pmc/articles/PMC8389888/ /pubmed/34232047 http://dx.doi.org/10.1021/acs.jpcb.1c01986 Text en © 2021 American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Zheng, Bin
Avni, Yael
Andelman, David
Podgornik, Rudolf
Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title_full Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title_fullStr Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title_full_unstemmed Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title_short Phase Separation of Polyelectrolytes: The Effect of Charge Regulation
title_sort phase separation of polyelectrolytes: the effect of charge regulation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389888/
https://www.ncbi.nlm.nih.gov/pubmed/34232047
http://dx.doi.org/10.1021/acs.jpcb.1c01986
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