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Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study
It is presently unknown whether imported cases of the 2019 coronavirus disease (COVID-19) have different characteristics when compared with local cases. To compare the clinical characteristics of local cases of COVID-19 in China compared with those imported from abroad. This was a retrospective stud...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389952/ https://www.ncbi.nlm.nih.gov/pubmed/34449458 http://dx.doi.org/10.1097/MD.0000000000026933 |
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author | Liu, Jing-He Chang, Yu-Fei Ma, Shan-Fang Wang, Ling-Hang |
author_facet | Liu, Jing-He Chang, Yu-Fei Ma, Shan-Fang Wang, Ling-Hang |
author_sort | Liu, Jing-He |
collection | PubMed |
description | It is presently unknown whether imported cases of the 2019 coronavirus disease (COVID-19) have different characteristics when compared with local cases. To compare the clinical characteristics of local cases of COVID-19 in China compared with those imported from abroad. This was a retrospective study of confirmed cases of COVID-19 admitted at the Beijing Ditan Fever Emergency Department between February 29(th), 2020, and March 27(th), 2020. The clinical characteristics of the patients were compared between local and imported cases. Compared with local cases, the imported cases were younger (27.3 ± 11.7 vs. 43.6 ± 22.2 years, P < .001), had a shorter interval from disease onset to admission (1.0 (0.0–2.0) vs 4.0 (2.0–7.0) days, P < .001), lower frequencies of case contact (17.4% vs 94.1%, P < .001), fever (39.1% vs 82.4%, P < .001), cough (33.3% vs 51.0%, P = .03), dyspnea (1.9% vs 11.8%, P = .01), fatigue (7.5% vs. 27.5%, P = 0.001), muscle ache (4.7% vs. 25.5%, P < 0.001), and comorbidities (P < .05). The imported cases were less severe than the local cases, with 40.4% versus 5.9% mild cases, 2.8% versus 15.7% severe cases, and no critical cases (P < .001). The length of hospital stay was longer in imported cases than in local cases (32.3 ± 14.5 vs 21.7 ± 11.2 days, P < .001). The imported cases showed smaller biochemical perturbations than the local cases. More imported cases had no sign of pneumonia at computed tomography (45.0% vs 14.9%, P = .001), and none had pleural effusion (0% vs 14.9%, P < .001). Compared with local cases, the imported cases of COVID-19 presented with milder disease and less extensive symptoms and signs. |
format | Online Article Text |
id | pubmed-8389952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-83899522021-09-02 Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study Liu, Jing-He Chang, Yu-Fei Ma, Shan-Fang Wang, Ling-Hang Medicine (Baltimore) 4900 It is presently unknown whether imported cases of the 2019 coronavirus disease (COVID-19) have different characteristics when compared with local cases. To compare the clinical characteristics of local cases of COVID-19 in China compared with those imported from abroad. This was a retrospective study of confirmed cases of COVID-19 admitted at the Beijing Ditan Fever Emergency Department between February 29(th), 2020, and March 27(th), 2020. The clinical characteristics of the patients were compared between local and imported cases. Compared with local cases, the imported cases were younger (27.3 ± 11.7 vs. 43.6 ± 22.2 years, P < .001), had a shorter interval from disease onset to admission (1.0 (0.0–2.0) vs 4.0 (2.0–7.0) days, P < .001), lower frequencies of case contact (17.4% vs 94.1%, P < .001), fever (39.1% vs 82.4%, P < .001), cough (33.3% vs 51.0%, P = .03), dyspnea (1.9% vs 11.8%, P = .01), fatigue (7.5% vs. 27.5%, P = 0.001), muscle ache (4.7% vs. 25.5%, P < 0.001), and comorbidities (P < .05). The imported cases were less severe than the local cases, with 40.4% versus 5.9% mild cases, 2.8% versus 15.7% severe cases, and no critical cases (P < .001). The length of hospital stay was longer in imported cases than in local cases (32.3 ± 14.5 vs 21.7 ± 11.2 days, P < .001). The imported cases showed smaller biochemical perturbations than the local cases. More imported cases had no sign of pneumonia at computed tomography (45.0% vs 14.9%, P = .001), and none had pleural effusion (0% vs 14.9%, P < .001). Compared with local cases, the imported cases of COVID-19 presented with milder disease and less extensive symptoms and signs. Lippincott Williams & Wilkins 2021-08-27 /pmc/articles/PMC8389952/ /pubmed/34449458 http://dx.doi.org/10.1097/MD.0000000000026933 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 4900 Liu, Jing-He Chang, Yu-Fei Ma, Shan-Fang Wang, Ling-Hang Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title | Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title_full | Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title_fullStr | Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title_full_unstemmed | Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title_short | Comparative study on the clinical characteristics of local cases of COVID-19 and imported cases from abroad: A retrospective cohort study |
title_sort | comparative study on the clinical characteristics of local cases of covid-19 and imported cases from abroad: a retrospective cohort study |
topic | 4900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389952/ https://www.ncbi.nlm.nih.gov/pubmed/34449458 http://dx.doi.org/10.1097/MD.0000000000026933 |
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