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Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis

One of major causes of cervical central stenosis (CCS) is thickened change of cervical ligament flavum (CLF). The association of a morphological parameter called cervical ligament flavum thickness (CLFT) with CCS has not been reported yet. Thus, the purpose of this research was to investigate the re...

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Autores principales: Jeong, Hye-Won, Yi, Jungmin, Lee, Sooho, Park, Sukhee, Kang, Keum Nae, Lee, Jonghyuk, Cho, Hyung Rae, Kim, Young Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389973/
https://www.ncbi.nlm.nih.gov/pubmed/34449510
http://dx.doi.org/10.1097/MD.0000000000027084
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author Jeong, Hye-Won
Yi, Jungmin
Lee, Sooho
Park, Sukhee
Kang, Keum Nae
Lee, Jonghyuk
Cho, Hyung Rae
Kim, Young Uk
author_facet Jeong, Hye-Won
Yi, Jungmin
Lee, Sooho
Park, Sukhee
Kang, Keum Nae
Lee, Jonghyuk
Cho, Hyung Rae
Kim, Young Uk
author_sort Jeong, Hye-Won
collection PubMed
description One of major causes of cervical central stenosis (CCS) is thickened change of cervical ligament flavum (CLF). The association of a morphological parameter called cervical ligament flavum thickness (CLFT) with CCS has not been reported yet. Thus, the purpose of this research was to investigate the relationship between CCS and CFJT. Data were obtained from 88 patients with CCS. A total of 87 normal controls also underwent cervical spine magnetic resonance imaging (CSMRI). All subjects underwent axial T2-weighted CSMRI. Using our picture archiving and communications system, thickness of ligament flavum of the cervical spine at C6/7 level was analyzed. The mean CLFT was 1.41 ± 0.24 mm in normal subjects and 2.09 ± 0.39 mm in patients with CCS. The CCS group was found to have significantly (P < .001) higher rate of CLFT than normal subjects. ROC curves were used to assess the usefulness of CLFT as a predictor of CCS. In the CCS group, the best practical cut off-point of CLFT was 1.71 mm (sensitivity = 90.9%; specificity = 90.8%), with AUC of 0.94 (95% confidence interval: 0.90--0.98). Greater CLFT values were associated with greater possibility of CCS. Thus, treating physician should carefully examine CLFT, as it can help diagnose CCS.
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spelling pubmed-83899732021-09-02 Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis Jeong, Hye-Won Yi, Jungmin Lee, Sooho Park, Sukhee Kang, Keum Nae Lee, Jonghyuk Cho, Hyung Rae Kim, Young Uk Medicine (Baltimore) 3300 One of major causes of cervical central stenosis (CCS) is thickened change of cervical ligament flavum (CLF). The association of a morphological parameter called cervical ligament flavum thickness (CLFT) with CCS has not been reported yet. Thus, the purpose of this research was to investigate the relationship between CCS and CFJT. Data were obtained from 88 patients with CCS. A total of 87 normal controls also underwent cervical spine magnetic resonance imaging (CSMRI). All subjects underwent axial T2-weighted CSMRI. Using our picture archiving and communications system, thickness of ligament flavum of the cervical spine at C6/7 level was analyzed. The mean CLFT was 1.41 ± 0.24 mm in normal subjects and 2.09 ± 0.39 mm in patients with CCS. The CCS group was found to have significantly (P < .001) higher rate of CLFT than normal subjects. ROC curves were used to assess the usefulness of CLFT as a predictor of CCS. In the CCS group, the best practical cut off-point of CLFT was 1.71 mm (sensitivity = 90.9%; specificity = 90.8%), with AUC of 0.94 (95% confidence interval: 0.90--0.98). Greater CLFT values were associated with greater possibility of CCS. Thus, treating physician should carefully examine CLFT, as it can help diagnose CCS. Lippincott Williams & Wilkins 2021-08-27 /pmc/articles/PMC8389973/ /pubmed/34449510 http://dx.doi.org/10.1097/MD.0000000000027084 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 3300
Jeong, Hye-Won
Yi, Jungmin
Lee, Sooho
Park, Sukhee
Kang, Keum Nae
Lee, Jonghyuk
Cho, Hyung Rae
Kim, Young Uk
Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title_full Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title_fullStr Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title_full_unstemmed Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title_short Prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
title_sort prognostic value of cervical ligamentum flavum thickness as a morphological parameter to predict cervical stenosis
topic 3300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389973/
https://www.ncbi.nlm.nih.gov/pubmed/34449510
http://dx.doi.org/10.1097/MD.0000000000027084
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