FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells

BACKGROUND: Angiogenesis is the process by which new blood vessels arise from pre-existing ones. Fibroblast growth factor-2 (FGF-2), a leading member of the FGF family of heparin-binding growth factors, contributes to normal as well as pathological angiogenesis. Pre-mRNA alternative splicing plays a...

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Detalles Bibliográficos
Autores principales: Jia, Tao, Jacquet, Thibault, Dalonneau, Fabien, Coudert, Pauline, Vaganay, Elisabeth, Exbrayat-Héritier, Chloé, Vollaire, Julien, Josserand, Véronique, Ruggiero, Florence, Coll, Jean-Luc, Eymin, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390225/
https://www.ncbi.nlm.nih.gov/pubmed/34433435
http://dx.doi.org/10.1186/s12915-021-01103-3

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