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The sirtuin 1 activator SRT1720 alleviated endotoxin-induced fulminant hepatitis in mice

The metabolic sensor sirtuin 1 (SIRT1) also functions as a checkpoint in inflammation, and SRT1720 is a highly active and selective SIRT1 activator shown to alleviate inflammatory injury in several recent experimental studies. In the present study, the potential effects and underlying mechanisms of...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Yang, Feng, Lin, Ling, Tang, Li, Li, Longjiang, Yang, Yongqiang, Liu, Dingrong, Zhang, Chong, Wu, Tong, Wei, Huijie, Zhang, Xiaoming, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390304/
https://www.ncbi.nlm.nih.gov/pubmed/33678756
http://dx.doi.org/10.1538/expanim.20-0014