CRIP1 cooperates with BRCA2 to drive the nuclear enrichment of RAD51 and to facilitate homologous repair upon DNA damage induced by chemotherapy

Homologous recombination (HR) repair is an important determinant of chemosensitivity. However, the mechanisms underlying HR regulation remain largely unknown. Cysteine-rich intestinal protein 1 (CRIP1) is a member of the LIM/double-zinc finger protein family and is overexpressed and associated with...

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Detalles Bibliográficos
Autores principales: Sun, Huiying, Zhou, Rui, Zheng, Yannan, Wen, Zhaowei, Zhang, Dingling, Zeng, Dongqiang, Wu, Jianhua, Huang, Zhenhua, Rong, Xiaoxiang, Huang, Na, Sun, Li, Bin, Jianping, Liao, Yulin, Shi, Min, Liao, Wangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390368/
https://www.ncbi.nlm.nih.gov/pubmed/34262130
http://dx.doi.org/10.1038/s41388-021-01932-0

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