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SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling

BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-induced inflammatory responses are largely responsible for the death of novel coronavirus disease 2019 (COVID-19) patients. However, the mechanism by which SARS-CoV-2 triggers inflammatory responses remains unclear. H...

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Detalles Bibliográficos
Autores principales:	Li, Fei, Li, Jingyao, Wang, Pei-Hui, Yang, Nanyan, Huang, Junyu, Ou, Jinxin, Xu, Ting, Zhao, Xin, Liu, Taoshu, Huang, Xueying, Wang, Qinghuan, Li, Miao, Yang, Le, Lin, Yunchen, Cai, Ying, Chen, Haisheng, Zhang, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390448/ https://www.ncbi.nlm.nih.gov/pubmed/34461258 http://dx.doi.org/10.1016/j.bbadis.2021.166260

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