Cargando…
Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes
Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (ClinicalTrials.gov, NCT02931071) the safety and efficacy of filgrastim and plerixafor for mobilization of HSPCs and...
Autores principales: | Sevilla, Julián, Navarro, Susana, Rio, Paula, Sánchez-Domínguez, Rebeca, Zubicaray, Josune, Gálvez, Eva, Merino, Eva, Sebastián, Elena, Azqueta, Carmen, Casado, José A., Segovia, José C., Alberquilla, Omaira, Bogliolo, Massimo, Román-Rodríguez, Francisco J., Giménez, Yari, Larcher, Lise, Salgado, Rocío, Pujol, Roser M., Hladun, Raquel, Castillo, Ana, Soulier, Jean, Querol, Sergi, Fernández, Jesús, Schwartz, Jonathan, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Surralles, Jordi, Díaz-de-Heredia, Cristina, Bueren, Juan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390450/ https://www.ncbi.nlm.nih.gov/pubmed/34485595 http://dx.doi.org/10.1016/j.omtm.2021.06.001 |
Ejemplares similares
-
Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia
por: Casado, José A., et al.
Publicado: (2022) -
TALEN mediated gene editing in a mouse model of Fanconi anemia
por: Pino-Barrio, Maria José, et al.
Publicado: (2020) -
Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia
por: Lasaga, Miren, et al.
Publicado: (2023) -
Next-generation Sequencing in Bone Marrow Failure Syndromes and Isolated Cytopenias: Experience of the Spanish Network on Bone Marrow Failure Syndromes
por: Gálvez, Eva, et al.
Publicado: (2021) -
Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells
por: Valeri, Antonio, et al.
Publicado: (2010)