Cargando…

MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor

The long noncoding RNA called MIR22 host gene (MIR22HG) was previously identified as a tumor suppressor in several cancers. However, the biological function of MIR22HG in breast cancer remains unknown. In this study, we aimed to determine the function and molecular mechanism of MIR22HG in breast can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Xiaochong, Ye, Danrong, Hua, Kaiyao, Song, Hongming, Luo, Qifeng, Munankarmy, Amik, Liu, Diya, Zhou, Baian, Zheng, Wenfang, Zhou, Xiqian, Ji, Changle, Wang, Xuehui, Yu, Yunhe, Fang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390479/ https://www.ncbi.nlm.nih.gov/pubmed/34446703 http://dx.doi.org/10.1038/s41419-021-04105-9

Ejemplares similares

Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis
por: Ji, Changle, et al.
Publicado: (2021)

VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer
por: Song, Hongming, et al.
Publicado: (2019)

The Role of miR-640: A Potential Suppressor in Breast Cancer via Wnt7b/β-catenin Signaling Pathway
por: Tang, Chun, et al.
Publicado: (2021)

miR-186-ANXA9 signaling inhibits tumorigenesis in breast cancer
por: Wang, Zhongrui, et al.
Publicado: (2023)

DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP
por: Ye, Danrong, et al.
Publicado: (2023)

Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

Correction to: Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

Circular RNA circRPPH1 promotes breast cancer progression via circRPPH1-miR-512-5p-STAT1 axis
por: Huang, Yixiang, et al.
Publicado: (2021)

Circular RNA_0006014 promotes breast cancer progression through sponging miR-885-3p to regulate NTRK2 and PIK3/AKT pathway
por: Zhou, Xiqian, et al.
Publicado: (2022)

Tumor-Derived circRNAs as Circulating Biomarkers for Breast Cancer
por: Yu, Yunhe, et al.
Publicado: (2022)

Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer
por: Hua, Kaiyao, et al.
Publicado: (2020)

CircRNF10-DHX15 interaction suppressed breast cancer progression by antagonizing DHX15-NF-κB p65 positive feedback loop
por: Zheng, Wenfang, et al.
Publicado: (2023)

MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer
por: Xu, Juan, et al.
Publicado: (2020)

Correction: MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer
por: Xu, Juan, et al.
Publicado: (2023)

MicroRNA-301b promotes cell proliferation and apoptosis resistance in triple-negative breast cancer by targeting CYLD
por: Song, Hongming, et al.
Publicado: (2018)

Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma
por: Zhang, Dong-Yan, et al.
Publicado: (2018)

Mir-30b-5p Promotes Proliferation, Migration, and Invasion of Breast Cancer Cells via Targeting ASPP2
por: Wu, Tianqi, et al.
Publicado: (2020)

Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer
por: Yu, Tian, et al.
Publicado: (2014)

Clinicopathological Significance of Large Tumor Suppressor (LATS) Expression in Gastric Cancer
por: Son, Myoung Won, et al.
Publicado: (2017)

MIR22HG regulates miR-486/PTEN axis in bladder cancer to promote cell proliferation
por: Tang, Qisheng, et al.
Publicado: (2020)

Prognostic values of long non-coding RNA MIR22HG for patients with hepatocellular carcinoma after hepatectomy
por: Dong, Yuan, et al.
Publicado: (2017)

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
por: Paramasivam, Murugan, et al.
Publicado: (2011)

The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation
por: Aylon, Yael, et al.
Publicado: (2016)

The Function of circRNA-0047604 in Regulating the Tumor Suppressor Gene DACH1 in Breast Cancer
por: Zhao, Bingkun, et al.
Publicado: (2022)

Emerging impact of the long noncoding RNA MIR22HG on proliferation and apoptosis in multiple human cancers
por: Zhang, Le, et al.
Publicado: (2020)

Long noncoding RNA MIR31HG abrogates the availability of tumor suppressor microRNA-361 for the growth of osteosarcoma
por: Sun, Yongjie, et al.
Publicado: (2019)

Long non-coding RNA Mir22hg-derived miR-22-3p promotes skeletal muscle differentiation and regeneration by inhibiting HDAC4
por: Li, Rongyang, et al.
Publicado: (2021)

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice
por: Siam, Rania, et al.
Publicado: (2009)

AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2
por: Philippe, Chloé, et al.
Publicado: (2018)

LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer
por: Shen, Zhengchao, et al.
Publicado: (2021)

MiR-22 as a metabolic silencer and liver tumor suppressor
por: Wang, Lijun, et al.
Publicado: (2020)

MiR-93 enhances angiogenesis and metastasis by targeting LATS2
por: Fang, Ling, et al.
Publicado: (2012)

MiR-429 Involves in the Pathogenesis of Colorectal Cancer via Directly Targeting LATS2
por: Chen, Xia, et al.
Publicado: (2020)

LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway
por: Long, Hui, et al.
Publicado: (2021)

lncRNA MIR22HG-Derived miR-22-5p Enhances the Radiosensitivity of Hepatocellular Carcinoma by Increasing Histone Acetylation Through the Inhibition of HDAC2 Activity
por: Jin, Qiao, et al.
Publicado: (2021)

LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR‐10a‐5p/NCOR2 axis in hepatocellular carcinoma cells
por: Wu, Yangjun, et al.
Publicado: (2019)

Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling
por: Han, Mingzhi, et al.
Publicado: (2020)

Yeast Cell-Based Transport Assay for the Functional Characterization of Human 4F2hc-LAT1 and ‐LAT2, and LAT1 and LAT2 Substrates and Inhibitors
por: Kantipudi, Satish, et al.
Publicado: (2021)

LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment
por: Tye, Coralee E., et al.
Publicado: (2022)

Association of MIR17HG and MIR155HG gene variants with steroid-induced osteonecrosis of the femoral head in the population of northern China
por: Liu, Tingting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fcc2lt7unk4h7viltd9uqv5laq