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Interaction of spindle assembly factor TPX2 with importins-α/β inhibits protein phase separation

The microtubule-based mitotic spindle is responsible for equally partitioning the genome during each cell division, and its assembly is executed via several microtubule nucleation pathways. Targeting Protein for XKlp2 (TPX2) stimulates the branching microtubule nucleation pathway, where new microtub...

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Detalles Bibliográficos
Autores principales:	Safari, Mohammad S., King, Matthew R., Brangwynne, Clifford P., Petry, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390506/ https://www.ncbi.nlm.nih.gov/pubmed/34302807 http://dx.doi.org/10.1016/j.jbc.2021.100998

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