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Design of phase 2 study of TAS-115, a novel oral multi-kinase inhibitor, in patients with idiopathic pulmonary fibrosis
BACKGROUND: TAS-115, a novel multi-kinase inhibitor, demonstrated antifibrotic effects in vitro and in vivo. METHODS: This is an open-label, intra-patient comparison, exploratory phase 2 study of TAS-115 to evaluate the efficacy and safety in idiopathic pulmonary fibrosis (IPF) patients when orally...
Autores principales: | Nishioka, Yasuhiko, Homma, Sakae, Okubo, Takahito, Azuma, Arata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390536/ https://www.ncbi.nlm.nih.gov/pubmed/34471721 http://dx.doi.org/10.1016/j.conctc.2021.100832 |
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