Clerodane-type Diterpene Glycosides from Dicranopteris pedata

Three new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol (2), (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranos...

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Detalles Bibliográficos
Autores principales: Gao, Bei-Bei, Ou, Yu-Fei, Zhu, Qin-Feng, Zhou, Zhi-Ping, Deng, Zhen-Tao, Li, Meng, Zhao, Qin-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390628/
https://www.ncbi.nlm.nih.gov/pubmed/34089490
http://dx.doi.org/10.1007/s13659-021-00315-y
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author Gao, Bei-Bei
Ou, Yu-Fei
Zhu, Qin-Feng
Zhou, Zhi-Ping
Deng, Zhen-Tao
Li, Meng
Zhao, Qin-Shi
author_facet Gao, Bei-Bei
Ou, Yu-Fei
Zhu, Qin-Feng
Zhou, Zhi-Ping
Deng, Zhen-Tao
Li, Meng
Zhao, Qin-Shi
author_sort Gao, Bei-Bei
collection PubMed
description Three new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol (2), (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-(13E)-2-oxoneocleroda-3,14-dien-13-ol (3), together with two known compounds 4 and 5 were isolated from Dicranopteris pedata. The structures of these compounds were elucidated by detailed spectroscopic analysis, and the absolute configuration of compound 2 was determined by ECD calculations. In addition, compound 1 exhibited weak inhibitory activities against SMMC-7721, MCF-7 and SW480. [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-021-00315-y.
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spelling pubmed-83906282021-09-14 Clerodane-type Diterpene Glycosides from Dicranopteris pedata Gao, Bei-Bei Ou, Yu-Fei Zhu, Qin-Feng Zhou, Zhi-Ping Deng, Zhen-Tao Li, Meng Zhao, Qin-Shi Nat Prod Bioprospect Original Article Three new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol (2), (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-(13E)-2-oxoneocleroda-3,14-dien-13-ol (3), together with two known compounds 4 and 5 were isolated from Dicranopteris pedata. The structures of these compounds were elucidated by detailed spectroscopic analysis, and the absolute configuration of compound 2 was determined by ECD calculations. In addition, compound 1 exhibited weak inhibitory activities against SMMC-7721, MCF-7 and SW480. [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-021-00315-y. Springer Singapore 2021-06-05 /pmc/articles/PMC8390628/ /pubmed/34089490 http://dx.doi.org/10.1007/s13659-021-00315-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Gao, Bei-Bei
Ou, Yu-Fei
Zhu, Qin-Feng
Zhou, Zhi-Ping
Deng, Zhen-Tao
Li, Meng
Zhao, Qin-Shi
Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title_full Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title_fullStr Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title_full_unstemmed Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title_short Clerodane-type Diterpene Glycosides from Dicranopteris pedata
title_sort clerodane-type diterpene glycosides from dicranopteris pedata
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390628/
https://www.ncbi.nlm.nih.gov/pubmed/34089490
http://dx.doi.org/10.1007/s13659-021-00315-y
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