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Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen

Full term pregnancy at an early age is the only factor known to consistently protect against breast cancer. Because hormone receptor positive progenitors in the human breast relay endocrine signaling, we here sought to determine whether an experimental mimicry of the third trimester surge of hormone...

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Detalles Bibliográficos
Autores principales: Rønnov-Jessen, Lone, Kim, Jiyoung, Goldhammer, Nadine, Klitgaard, Marie Christine, Smicius, Martynas, Bechmann, Marc Baker, Villadsen, René, Petersen, Ole William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390656/
https://www.ncbi.nlm.nih.gov/pubmed/34446796
http://dx.doi.org/10.1038/s41598-021-96785-8