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Optimal loading dose of meropenem before continuous infusion in critically ill patients: a simulation study
The aim of this study was to investigate optimal loading doses prior to continuous infusion of meropenem in critically ill patients. A previously published and successfully evaluated pharmacokinetic model of critically ill patients was used for stochastic simulations of virtual patients. Maintenance...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390684/ https://www.ncbi.nlm.nih.gov/pubmed/34446780 http://dx.doi.org/10.1038/s41598-021-96744-3 |