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Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo

Protein delivery with cell-penetrating peptide is opening up the possibility of using targets inside cells for therapeutic or biological applications; however, cell-penetrating peptide-mediated protein delivery commonly suffers from ineffective endosomal escape and low tolerance in serum, thereby li...

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Detalles Bibliográficos
Autores principales: Yu, Siyuan, Yang, Han, Li, Tingdong, Pan, Haifeng, Ren, Shuling, Luo, Guoxing, Jiang, Jinlu, Yu, Linqi, Chen, Binbing, Zhang, Yali, Wang, Shaojuan, Tian, Rui, Zhang, Tianying, Zhang, Shiyin, Chen, Yixin, Yuan, Quan, Ge, Shengxiang, Zhang, Jun, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390694/
https://www.ncbi.nlm.nih.gov/pubmed/34446736
http://dx.doi.org/10.1038/s41467-021-25448-z