Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

Congenital heart defects constitute the most common human birth defect, however understanding of how these disorders originate is limited by our ability to model the human heart accurately in vitro. Here we report a method to generate developmentally relevant human heart organoids by self-assembly u...

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Detalles Bibliográficos
Autores principales: Lewis-Israeli, Yonatan R., Wasserman, Aaron H., Gabalski, Mitchell A., Volmert, Brett D., Ming, Yixuan, Ball, Kristen A., Yang, Weiyang, Zou, Jinyun, Ni, Guangming, Pajares, Natalia, Chatzistavrou, Xanthippi, Li, Wen, Zhou, Chao, Aguirre, Aitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390749/
https://www.ncbi.nlm.nih.gov/pubmed/34446706
http://dx.doi.org/10.1038/s41467-021-25329-5

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