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Cation competition and recruitment around the c-kit1 G-quadruplex using polarizable simulations

Nucleic acid-ion interactions are fundamentally important to the physical, energetic, and conformational properties of DNA and RNA. These interactions help fold and stabilize highly ordered secondary and tertiary structures, such as G-quadruplexes (GQs), which are functionally relevant in telomeres,...

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Detalles Bibliográficos
Autores principales: Salsbury, Alexa M., Lemkul, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390831/
https://www.ncbi.nlm.nih.gov/pubmed/33794153
http://dx.doi.org/10.1016/j.bpj.2021.03.022