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Encapsulation state of messenger RNA inside lipid nanoparticles

Understanding the structure of messenger RNA (mRNA) lipid nanoparticles, and specifically the microenvironment of the mRNA molecules within these entities, is fundamental to advancing their biomedical potential. Here, we show that a permeating cationic dye, thionine, can serve as a cryogenic electro...

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Detalles Bibliográficos
Autores principales: Brader, Mark L., Williams, Sean J., Banks, Jessica M., Hui, Wong H., Zhou, Z. Hong, Jin, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390897/
https://www.ncbi.nlm.nih.gov/pubmed/33773963
http://dx.doi.org/10.1016/j.bpj.2021.03.012