Cargando…

Impact of Glucocorticoid on a Cellular Model of Parkinson’s Disease: Oxidative Stress and Mitochondrial Function

Stress seems to contribute to the neuropathology of Parkinson’s disease (PD), possibly by dysregulation of the hypothalamic–pituitary–adrenal axis. Oxidative distress and mitochondrial dysfunction are key factors involved in the pathophysiology of PD and neuronal glucocorticoid-induced toxicity. Ani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Claros, Silvia, Gil, Antonio, Martinelli, Mauro, Valverde, Nadia, Lara, Estrella, Boraldi, Federica, Pavia, Jose, Martín-Montañez, Elisa, Garcia-Fernandez, María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391158/ https://www.ncbi.nlm.nih.gov/pubmed/34439724 http://dx.doi.org/10.3390/brainsci11081106

Ejemplares similares

Neuronal Metabolism and Neuroprotection: Neuroprotective Effect of Fingolimod on Menadione-Induced Mitochondrial Damage
por: Gil, Antonio, et al.
Publicado: (2020)

Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease
por: Martín-Montañez, Elisa, et al.
Publicado: (2021)

Insulin-like Growth Factor II Prevents MPP+ and Glucocorticoid Mitochondrial-Oxidative and Neuronal Damage in Dopaminergic Neurons
por: Claros, Silvia, et al.
Publicado: (2021)

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids
por: Martín-Montañez, E., et al.
Publicado: (2017)

Relationship Between Mitochondrial Structure and Bioenergetics in Pseudoxanthoma elasticum Dermal Fibroblasts
por: Lofaro, Francesco Demetrio, et al.
Publicado: (2020)

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease
por: Lualdi, Marta, et al.
Publicado: (2019)

Testing Cellular Proliferation Responses to Oxidative, Glucocorticoid and Metabolic Challenges in the Baboon
por: Adekunbi, Daniel, et al.
Publicado: (2020)

Impaired Mitochondrial Morphology and Functionality in Lonp1(wt/−) Mice
por: De Gaetano, Anna, et al.
Publicado: (2020)

Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis
por: Sionov, Ronit Vogt, et al.
Publicado: (2006)

Mitochondrial and Endoplasmic Reticulum Alterations in a Case of Amyotrophic Lateral Sclerosis Caused by TDP-43 A382T Mutation
por: Zanini, Giada, et al.
Publicado: (2022)

Inflammation in Parkinson’s disease: role of glucocorticoids
por: Herrero, María-Trinidad, et al.
Publicado: (2015)

Oxidative stress and cellular pathologies in Parkinson’s disease
por: Puspita, Lesly, et al.
Publicado: (2017)

Mitochondrial Glucocorticoid Receptors and Their Actions
por: Kokkinopoulou, Ioanna, et al.
Publicado: (2021)

C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson’s Disease
por: Sierra-Magro, Ana, et al.
Publicado: (2023)

Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes
por: Malaise, Olivier, et al.
Publicado: (2021)

Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson’s Disease
por: Rey, Federica, et al.
Publicado: (2021)

Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease
por: Jiménez-Delgado, Alicia, et al.
Publicado: (2021)

Glucocorticoid counteracts cellular mechanoresponses by LINC01569-dependent glucocorticoid receptor–mediated mRNA decay
por: Zhu, Huayu, et al.
Publicado: (2021)

Glucocorticoids Suppress Mitochondrial Oxidant Production via Upregulation of Uncoupling Protein 2 in Hyperglycemic Endothelial Cells
por: Gerö, Domokos, et al.
Publicado: (2016)

Proanthocyanidins-Mediated Nrf2 Activation Ameliorates Glucocorticoid-Induced Oxidative Stress and Mitochondrial Dysfunction in Osteoblasts
por: Chen, Liang, et al.
Publicado: (2020)

Cellular response against cytosolic leakage of mitochondrial DNA: insights into the pathology of Parkinson’s disease
por: Sakai, Akiko, et al.
Publicado: (2022)

Mitochondrial biogenesis, telomere length and cellular senescence in Parkinson’s disease and Lewy body dementia
por: Asghar, Muhammad, et al.
Publicado: (2022)

Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress
por: Naudi, Alba, et al.
Publicado: (2012)

Apoptosis in the Extraosseous Calcification Process
por: Boraldi, Federica, et al.
Publicado: (2021)

Cellular Oxidative Stress
por: Dossena, Silvia, et al.
Publicado: (2021)

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease
por: Al Shahrani, Mesfer, et al.
Publicado: (2017)

The Roles of Mitochondrial Folate Metabolism in Supporting Mitochondrial DNA Synthesis, Oxidative Phosphorylation, and Cellular Function
por: Xiu, Yuwen, et al.
Publicado: (2020)

GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2
por: Blanca Ramírez, Marian, et al.
Publicado: (2017)

Alteration of mitochondrial protein succinylation against cellular oxidative stress in cancer
por: Zhang, Jing, et al.
Publicado: (2022)

Cellular and biochemical actions of adrenal glucocorticoid hormones on rat thymic lymphocytes.
por: Young, D A, et al.
Publicado: (1981)

The SRSF4–GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy
por: Larrasa-Alonso, Javier, et al.
Publicado: (2021)

High-Resolution Respirometry Reveals MPP(+) Mitochondrial Toxicity Mechanism in a Cellular Model of Parkinson’s Disease
por: Risiglione, Pierpaolo, et al.
Publicado: (2020)

Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease
por: Matsui, Hideaki, et al.
Publicado: (2021)

The “Elastic Perspective” of SARS-CoV-2 Infection and the Role of Intrinsic and Extrinsic Factors
por: Boraldi, Federica, et al.
Publicado: (2022)

Dermal Alterations in Clinically Unaffected Skin of Pseudoxanthoma elasticum Patients
por: Boraldi, Federica, et al.
Publicado: (2021)

Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress
por: Ciccone, Sarah, et al.
Publicado: (2013)

Oxidative Stress, Mitochondrial Dysfunction, and Neuroprotection of Polyphenols with Respect to Resveratrol in Parkinson’s Disease
por: Kung, Heng-Chung, et al.
Publicado: (2021)

The Effect of Glucocorticoids on TAF1 Gene Transcription in X-linked Dystonia Parkinsonism
por: Cruz, Sam Ezrael Dela, et al.
Publicado: (2022)

Serum Biomarkers in Differential Diagnosis of Idiopathic Pulmonary Fibrosis and Connective Tissue Disease-Associated Interstitial Lung Disease
por: Cabrera Cesar, Eva, et al.
Publicado: (2021)

A Jack of All Trades: Impact of Glucocorticoids on Cellular Cross-Talk in Osteoimmunology
por: Ahmad, Mubashir, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3tpu6f3v8k0kpcskfp1fai59gg