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Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function

Ewing sarcoma (EwS) is an aggressive pediatric cancer of bone and soft tissues characterized by scant T cell infiltration and predominance of immunosuppressive myeloid cells. Given the important roles of extracellular vesicles (EVs) in cancer-host crosstalk, we hypothesized that EVs secreted by EwS...

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Detalles Bibliográficos
Autores principales: Gassmann, Hendrik, Schneider, Kira, Evdokimova, Valentina, Ruzanov, Peter, Schober, Sebastian J., Xue, Busheng, von Heyking, Kristina, Thiede, Melanie, Richter, Guenther H. S., Pfaffl, Michael W., Noessner, Elfriede, Stein, Lincoln D., Sorensen, Poul H., Burdach, Stefan E. G., Thiel, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391167/
https://www.ncbi.nlm.nih.gov/pubmed/34440851
http://dx.doi.org/10.3390/cells10082081