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Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma

SIMPLE SUMMARY: In this study, drug combination screening was used to design a multidrug combination consisting of repurposed drugs to treat sunitinib-resistant clear cell renal cell carcinoma. In the frame of this project, the multidrug combination has been optimized and validated and an insight in...

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Detalles Bibliográficos
Autores principales: Rausch, Magdalena, Rutz, Adriano, Allard, Pierre-Marie, Delucinge-Vivier, Céline, Docquier, Mylène, Dormond, Olivier, Dyson, Paul J., Wolfender, Jean-Luc, Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391235/
https://www.ncbi.nlm.nih.gov/pubmed/34439134
http://dx.doi.org/10.3390/cancers13163978