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Bayesian Sequential Monitoring of Single-Arm Trials: A Comparison of Futility Rules Based on Binary Data
In clinical trials, futility rules are widely used to monitor the study while it is in progress, with the aim of ensuring early termination if the experimental treatment is unlikely to provide the desired level of efficacy. In this paper, we focus on Bayesian strategies to perform interim analyses i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391240/ https://www.ncbi.nlm.nih.gov/pubmed/34444562 http://dx.doi.org/10.3390/ijerph18168816 |