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Unraveling Human AQP5-PIP Molecular Interaction and Effect on AQP5 Salivary Glands Localization in SS Patients

Saliva secretion requires effective translocation of aquaporin 5 (AQP5) water channel to the salivary glands (SGs) acinar apical membrane. Patients with Sjögren’s syndrome (SS) display abnormal AQP5 localization within acinar cells from SGs that correlate with sicca manifestation and glands hypofunc...

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Detalles Bibliográficos
Autores principales: Chivasso, Clara, Nesverova, Veronika, Järvå, Michael, Blanchard, Anne, Rose, Kristie L, Öberg, Fredrik Kryh, Wang, Zhen, Martin, Maud, Lhotellerie, Florent, Zindy, Egor, Junqueira, Bruna, Leroy, Karelle, Vanhollebeke, Benoit, Delforge, Valérie, Bolaky, Nargis, Perret, Jason, Soyfoo, Muhammad Shahnawaz, Moscato, Stefania, Baldini, Chiara, Chaumont, François, Mattii, Letizia, Schey, Kevin L, Myal, Yvonne, Törnroth-Horsefield, Susanna, Delporte, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391295/
https://www.ncbi.nlm.nih.gov/pubmed/34440877
http://dx.doi.org/10.3390/cells10082108