Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer

SIMPLE SUMMARY: Cancer, but also its treatment, can lead to a reprogramming of cellular metabolism. These changes are observable in metabolite abundances, which can be unbiasedly measured via mass spectrometry metabolomics. However, even when the metabolome changes strongly, a (mechanistic) interpre...

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Detalles Bibliográficos
Autores principales: Herrmann, Helena A., Rusz, Mate, Baier, Dina, Jakupec, Michael A., Keppler, Bernhard K., Berger, Walter, Koellensperger, Gunda, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391396/
https://www.ncbi.nlm.nih.gov/pubmed/34439283
http://dx.doi.org/10.3390/cancers13164130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391396/
https://www.ncbi.nlm.nih.gov/pubmed/34439283
http://dx.doi.org/10.3390/cancers13164130

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