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Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype
Apolipoprotein L1 (APOL1) high-risk genotypes (HRG), G1 and G2, increase the risk of various non-diabetic kidney diseases in the African population. To date, the precise mechanisms by which APOL1 risk variants induce injury on podocytes and other kidney cells remain unclear. Trying to unravel these...
Autores principales: | Ekulu, Pepe M., Adebayo, Oyindamola C., Decuypere, Jean-Paul, Bellucci, Linda, Elmonem, Mohamed A., Nkoy, Agathe B., Mekahli, Djalila, Bussolati, Benedetta, van den Heuvel, Lambertus P., Arcolino, Fanny O., Levtchenko, Elena N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391400/ https://www.ncbi.nlm.nih.gov/pubmed/34440683 http://dx.doi.org/10.3390/cells10081914 |
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