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The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders

Regenerative medicine is a dynamically developing field of human and veterinary medicine. The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment in experimental and preclinical studies with a satisfactory therapeutic effect. Year by year, the need for alternative treatme...

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Autores principales: Prządka, Przemysław, Buczak, Krzysztof, Frejlich, Ewelina, Gąsior, Ludwika, Suliga, Kamil, Kiełbowicz, Zdzisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391453/
https://www.ncbi.nlm.nih.gov/pubmed/34439807
http://dx.doi.org/10.3390/biom11081141
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author Prządka, Przemysław
Buczak, Krzysztof
Frejlich, Ewelina
Gąsior, Ludwika
Suliga, Kamil
Kiełbowicz, Zdzisław
author_facet Prządka, Przemysław
Buczak, Krzysztof
Frejlich, Ewelina
Gąsior, Ludwika
Suliga, Kamil
Kiełbowicz, Zdzisław
author_sort Prządka, Przemysław
collection PubMed
description Regenerative medicine is a dynamically developing field of human and veterinary medicine. The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment in experimental and preclinical studies with a satisfactory therapeutic effect. Year by year, the need for alternative treatments in veterinary medicine is increasing, and other applications for promising MSCs and their biological derivatives are constantly being sought. There is also an increase in demand for other methods of treating disease states, of which the classical treatment methods did not bring the desired results. Cell therapy can be a realistic option for treating human and animal diseases in the near future and therefore additional research is needed to optimize cell origins, numbers, or application methods in order to standardize the treatment process and assess its effects. The aim of the following work was to summarize available knowledge about stem cells in veterinary medicine and their possible application in the treatment of chosen musculoskeletal disorders in dogs and horses.
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spelling pubmed-83914532021-08-28 The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders Prządka, Przemysław Buczak, Krzysztof Frejlich, Ewelina Gąsior, Ludwika Suliga, Kamil Kiełbowicz, Zdzisław Biomolecules Review Regenerative medicine is a dynamically developing field of human and veterinary medicine. The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment in experimental and preclinical studies with a satisfactory therapeutic effect. Year by year, the need for alternative treatments in veterinary medicine is increasing, and other applications for promising MSCs and their biological derivatives are constantly being sought. There is also an increase in demand for other methods of treating disease states, of which the classical treatment methods did not bring the desired results. Cell therapy can be a realistic option for treating human and animal diseases in the near future and therefore additional research is needed to optimize cell origins, numbers, or application methods in order to standardize the treatment process and assess its effects. The aim of the following work was to summarize available knowledge about stem cells in veterinary medicine and their possible application in the treatment of chosen musculoskeletal disorders in dogs and horses. MDPI 2021-08-02 /pmc/articles/PMC8391453/ /pubmed/34439807 http://dx.doi.org/10.3390/biom11081141 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Prządka, Przemysław
Buczak, Krzysztof
Frejlich, Ewelina
Gąsior, Ludwika
Suliga, Kamil
Kiełbowicz, Zdzisław
The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title_full The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title_fullStr The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title_full_unstemmed The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title_short The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders
title_sort role of mesenchymal stem cells (mscs) in veterinary medicine and their use in musculoskeletal disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391453/
https://www.ncbi.nlm.nih.gov/pubmed/34439807
http://dx.doi.org/10.3390/biom11081141
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