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Mechanisms of Smoothened Regulation in Hedgehog Signaling

The seven-transmembrane protein, Smoothened (SMO), has shown to be critical for the hedgehog (HH) signal transduction on the cell membrane (and the cilium in vertebrates). SMO is subjected to multiple types of post-translational regulations, including phosphorylation, ubiquitination, and sumoylation...

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Detalles Bibliográficos
Autores principales:	Zhang, Jie, Liu, Zulong, Jia, Jianhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391454/ https://www.ncbi.nlm.nih.gov/pubmed/34440907 http://dx.doi.org/10.3390/cells10082138

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